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David Orlikowski Selected Research

Neuromuscular Diseases (Neuromuscular Disease)

3/2019Comparison of Two Cough-Augmentation Techniques Delivered by a Home Ventilator in Subjects With Neuromuscular Disease.
12/2017Invasive versus non-invasive ventilation for acute respiratory failure in neuromuscular disease and chest wall disorders.
4/2017Prognostic value of nocturnal hypoventilation in neuromuscular patients.
10/2016Factors influencing compliance with non-invasive ventilation at long-term in patients with myotonic dystrophy type 1: A prospective cohort.
2/2016Home monitoring of daytime mouthpiece ventilation effectiveness in patients with neuromuscular disease.
1/2016Comparison of ventilator-integrated end-tidal CO2 and transcutaneous CO2 monitoring in home-ventilated neuromuscular patients.
1/2016Impact of invasive ventilation on survival when non-invasive ventilation is ineffective in patients with Duchenne muscular dystrophy: A prospective cohort.
9/2014Evaluation of ventilators for mouthpiece ventilation in neuromuscular disease.
1/2014Long-term mechanical ventilation equipment for neuromuscular patients: meeting the expectations of patients and prescribers.
5/2013Patient-controlled positive end-expiratory pressure with neuromuscular disease: effect on speech in patients with tracheostomy and mechanical ventilation support.
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David Orlikowski Research Topics

Disease

17Respiratory Insufficiency (Respiratory Failure)
09/2020 - 01/2004
15Neuromuscular Diseases (Neuromuscular Disease)
03/2019 - 01/2004
14Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
01/2021 - 04/2008
7Muscular Dystrophies (Muscular Dystrophy)
01/2021 - 08/2009
7Hypoventilation
01/2021 - 12/2014
6Glycogen Storage Disease Type II (Pompe's Disease)
11/2020 - 07/2011
6Guillain-Barre Syndrome
09/2020 - 11/2005
5Cough
01/2021 - 01/2014
5Pneumonia (Pneumonitis)
09/2020 - 12/2006
4Heart Failure
12/2018 - 10/2013
4Hypercapnia
04/2017 - 08/2015
3Myotonic Dystrophy (Dystrophia Myotonica)
11/2018 - 10/2016
3Septic Shock (Toxic Shock Syndrome)
06/2013 - 11/2003
2Deglutition Disorders (Dysphagia)
01/2021 - 01/2016
2Cardiovascular Diseases (Cardiovascular Disease)
07/2018 - 01/2018
2Sarcoglycanopathies
01/2018 - 12/2014
2Infections
11/2016 - 11/2011
2Sepsis (Septicemia)
06/2013 - 02/2012
2Muscular Diseases (Myopathy)
07/2011 - 12/2008
1Malnutrition (Nutritional Deficiencies)
01/2021
1Nervous System Diseases (Neurological Disorders)
01/2019
1Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
01/2018
1Bundle-Branch Block (Fascicular Block)
01/2018
1Ventilator-Associated Pneumonia
12/2017
1Barotrauma
12/2017
1Inborn Genetic Diseases (Disease, Hereditary)
11/2016
1Cardiac Sudden Death (Sudden Cardiac Arrest)
11/2016
1Sleep Apnea Syndromes (Sleep Apnea)
08/2015
1Motor Neuron Disease (Primary Lateral Sclerosis)
12/2014
1Polyneuropathies (Polyneuropathy)
11/2011
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
11/2011
1Miller Fisher Syndrome (Fisher Syndrome)
11/2011
1Facial Paralysis (Facial Palsy)
04/2011
1Cardiogenic Shock
02/2010
1Myocarditis (Carditis)
02/2010
1Cardiomyopathies (Cardiomyopathy)
01/2010
1Autonomic Nervous System Diseases (Dysautonomia)
08/2009
1Disorders of Excessive Somnolence (Hypersomnia)
08/2009
1Human Influenza (Influenza)
01/2009
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2009
1Adrenal Insufficiency (Adrenal Gland Hypofunction)
05/2008
1Aspiration Pneumonia
12/2007
1Experimental Autoimmune Neuritis
11/2005
1Autoimmune Diseases (Autoimmune Disease)
11/2005
1Necrosis
11/2003

Drug/Important Bio-Agent (IBA)

5DystrophinIBA
01/2021 - 04/2008
4Proteins (Proteins, Gene)FDA Link
01/2018 - 04/2008
3human GAA protein (Myozyme)FDA Link
11/2020 - 07/2011
3Oxygen (Dioxygen)IBA
12/2017 - 02/2016
2Anti-Bacterial Agents (Antibiotics)IBA
01/2019 - 12/2017
2AcidsIBA
01/2019 - 11/2018
2GlucosidasesIBA
11/2018 - 07/2011
2Sarcoglycans (beta Sarcoglycan)IBA
01/2018 - 12/2014
2AntibodiesIBA
11/2011 - 01/2009
2Hydrocortisone (Cortisol)FDA LinkGeneric
08/2009 - 05/2008
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2021
1Natriuretic PeptidesIBA
12/2018
1GasesIBA
01/2016
1alpha-Glucosidases (Acid Maltase)IBA
05/2015
1Carbon DioxideIBA
09/2012
1Lactic Acid (Lactate)FDA LinkGeneric
02/2012
1Immunoglobulin M (IgM)IBA
11/2011
1Immunoglobulin G (IgG)IBA
11/2011
1GangliosidesIBA
11/2011
1DNA (Deoxyribonucleic Acid)IBA
04/2011
1Modafinil (Provigil)FDA Link
08/2009
1Adrenocorticotropic Hormone (ACTH)FDA Link
08/2009
1Complement System Proteins (Complement)IBA
01/2009
1Anesthetics (Anesthetic Agents)IBA
12/2008
1PlacebosIBA
05/2008
1Adrenal Cortex Hormones (Corticosteroids)IBA
05/2008
1FludrocortisoneIBA
05/2008
1Macrophage Migration-Inhibitory FactorsIBA
11/2005
1CytokinesIBA
11/2005
1Monoclonal AntibodiesIBA
11/2005
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
11/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2003

Therapy/Procedure

24Artificial Respiration (Mechanical Ventilation)
01/2021 - 01/2004
8Noninvasive Ventilation
01/2021 - 01/2004
8Mechanical Ventilators (Ventilator)
09/2020 - 10/2008
8Tracheostomy
01/2019 - 02/2007
4Enzyme Replacement Therapy
11/2020 - 07/2011
3Therapeutics
03/2014 - 01/2010
2Length of Stay
12/2017 - 12/2007
2Resuscitation
06/2013 - 02/2012
2Positive-Pressure Respiration (Positive End-Expiratory Pressure)
05/2013 - 12/2007
1Gastrostomy
01/2021
1Intermittent Positive-Pressure Ventilation
12/2017
1Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
11/2016
1Replantation
11/2016
1Intermittent Positive-Pressure Breathing
01/2014
1Early Goal-Directed Therapy
02/2012
1Extracorporeal Membrane Oxygenation
02/2010
1Tracheotomy
12/2007